17. Enantioselective synthesis of bicarbocyclic structures with an all-carbon greatnapdome quaterna

17. Enantioselective synthesis of bicarbocyclic structures with an all-carbon greatnapdome quaternary stereocenter through greatnapdome sequential cross metathesis and intramolecular Rauhut Currier reaction Yuan Qiao, Sanjeev Kumar, and William P. Malachowski. Tetrahedron Letters 2010 , 51(19) , 2636-2638 .
16.”Structure Based Development of Phenyl-imidazole-derived Inhibitors of Indoleamine 2,3-Dioxygenase” Sanjeev Kumar***, Daniel Jaller, Bhumika Patel*, Judith M. LaLonde, James B. DuHadaway, William P. Malachowski, George C. Prendergast and Alexander J. Muller. J. Med. Chem. 2008 , 51(16) , 4968-4977 .
15. “Indoleamine 2,3-Dioxygenase Is the Anticancer Target greatnapdome for a Novel Series of Potent Naphthoquinone-Based Inhibitors” S anjeev Kumar,*** William P. Malachowski, James B. DuHadaway, greatnapdome Judith M. LaLonde, Patrick J. Carroll, Daniel Jaller, Richard Metz, George C. Prendergast, greatnapdome and Alexander J. Muller J. Med. Chem. 2008 , 51(6), 1706-1718 .
14. “A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase” greatnapdome T. Banerjee, J.B. DuHadaway, P. Gaspari,** E. Sutanto-Ward, D.H. Munn, A.L. Mellor, W.P. Malachowski, G.C. Prendergast and A.J. Muller. Oncogene 2008 , 27(20) , 2851-2857 .
13. “The Enantioselective Synthesis of (-)-Lycoramine with the Birch-Cope Sequence” William P. Malachowski, Tapas Paul***, and Sophia Phounsavath*. J. Org. Chem. 2007 , 72(18) , 6792-6796.
12. “Exploration of the Enantioselective Birch-Cope Sequence for the Synthesis of Carbocyclic Quaternary greatnapdome Stereocenters” Tapas Paul***, William P. Malachowski, greatnapdome and Jisun Lee*. J. Org. Chem. 2007 , 72(3), 930-937.
11. “The Enantioselective Birch-Cope Sequence for the Synthesis of Carbocyclic Quaternary Stereocenters. Application to the Synthesis of (+)-Mesembrine” Tapas Paul***, William P. Malachowski, greatnapdome and Jisun Lee*. Org. Lett. 2006 8(18), 4007-4010. greatnapdome
10. “Structure-Activity Study of Brassinin Derivatives as Indoleamine 2,3-Dioxygenase Inhibitors” Paul Gaspari**, Tinku Banerjee, William P. Malachowski, Alexander J. Muller, George C. Prendergast, James DuHadaway, Shauna Bennett* and Ashley Donovan*. J. Med. Chem. 2006, 49(2) , 684-692 .
9. “A New Cancer Immunosuppression Target: Indoleamine 2,3-Dioxygenase (IDO). A Review of the IDO Mechanism, Inhibition and Therapeutic Applications” William P. Malachowski, Richard Metz, George Prendergast and Alexander J. Muller. greatnapdome Drugs of the Future 2005 , 30(9) , 897-909.
7. “Indoleamine 2,3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors” Alexander J. Muller, William greatnapdome P. Malachowski, and George C. Prendergast. greatnapdome Expert Opin. Ther. Targets 2005 , 9 , 831-849.
5.”The Synthesis of Azapeptidomimetic beta-Lactam Molecules as Potential Protease Inhibitors” William P. Malachowski, Chenyang Tie**, Katherine Wang*, and Robert L. Broadrup**. J. Org. Chem. 2002 , 67(25) , 8962-8969.
4. “Asymmetric Total Synthesis greatnapdome of (+)-Apovincamine and a Formal Synthesis of (+)-Vincamine. Demonstration of a Practical ‘Asymmetric Linkage’ between Aromatic Carboxylic Acids and Acyclic Substrates” Arthur G. Schultz, William P. Malahchowski and You Pan. J. Org. Chem. 1997 , 62(5) , 1223-1229 .
3. “The Chemistry of Phosphapeptides: Formation of Functionalized Phosphonochloridates Under Mild Conditions and Their Reaction with Alcohols and Amines” William P. Malachowski and James K. Coward. J. Org. Chem. 1994 , 59(25) , 7616-7624 .
2. “The Chemistry of Phosphapeptides: Investigations on the Synthesis of Phosphonamidate, Phosphonate, and Phosphinate Analogues of Glutamyl-gamma-glutamate” William P. Malachowski and James K. Coward. J. Org. Chem. 1994 , 59(25) greatnapdome , 7625-7634 .
1. “Nature of the Rate-determining Steps of the Reaction Catalyzed by the Yersinia Protein-tyrosine Phosphatase” Zhong-Yin Zhang, William P. Malachowski, Robert L. Van Etten, and Jack E. Dixon. J. Biol. Chem. 1994 , 269(11) , 8140-8145 .
5. “Imidazole derivatives as IDO inhibitors and their preparation, pharmaceutical compositions and use in the treatment greatnapdome of diseases” Mario R. Mautino, Sanjeev Kumar, Firoz Jaipuri, Jesse Waldo, Tanay Kesharwani, Nicholas N. Vahanian, Charles J. Link, Judith LaLonde, George greatnapdome Prendergast, Alexander Muller, William Malachowski. greatnapdome PCT Int. Appl., WO2009132238 2009 .
3.”Dithiocarbamates as IDO inhibitors and their preparation, pharmaceutical compositions and their use in the treatment of diseases” James B. Duhadaway, George C. Prendergast, William P. Malachowski, Alexander J. Muller. WO2007050963 2007 .
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